EPO-derived 11-AA tissue-protective peptide

Ara-290 (Cibinetide).

An 11-amino-acid synthetic peptide derived from the helix B surface of erythropoietin (EPO). Engineered to bind the EPOR/CD131 heteromer without haematopoietic activity.

Key Information

CompoundARA290
Research categoryRegenerative Research
Available sizes10mg, 20mg, 30mg
PricingFrom £39
FormatLyophilised powder in sealed vial
Purity>99% by HPLC (Janoshik Analytical, batch-verified)
Intended useIn-vitro laboratory research only. Not for human consumption.

Chemical & Reference Data

Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.

Compound classSynthetic 11-amino-acid linear peptide derived from EPO helix B (Cibinetide)
Molecular formulaC51H82N16O20
Molecular weight1257.4 g/mol
CAS Registry Number1239358-86-1
Number of residues11
Amino acid sequenceQEQLERALNSS
Receptor / mechanismInnate Repair Receptor (EPO-βcR heteromer) agonist; non-erythropoietic.
Reported half-lifeReported ~2 minutes in human serum (very short).
SolubilityLyophilised powder reconstitutes in bacteriostatic water for laboratory use.
Storage (lyophilised)Stable at 2–8 °C lyophilised for 24+ months.
Storage (reconstituted)Reconstituted: store at 2–8 °C, use within 14 days.
Clinical / regulatory statusPhase 2 in published research.

Research Profile

  • 11-amino-acid EPO-derived peptide
  • Non-haematopoietic EPO analogue
  • Studied in tissue-repair models
  • Third-party purity tested
  • Research use only

ARA290 (Cibinetide) is a synthetic 11-amino-acid peptide derived from the B-helix of erythropoietin. Characterised in the literature for its binding to the innate repair receptor complex (EPOR/βcR) without haematopoietic activity. Supplied as lyophilised powder for in-vitro research use only.

The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.

Laboratory Handling

ARA290 is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.

Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.

StateTemperatureShelf life
Lyophilised2–8 °C or −20 °CUp to 24 months
Reconstituted2–8 °C4–6 weeks typical

Purity & Verification

Every batch of ARA290 we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.

Latest Janoshik report for ARA-290 10mg · task #237376 · analysed 28 Sep 2026

This report is for the batch, not the size. Janoshik’s HPLC test measures what the compound is and how pure it is, and its quantification confirms the amount in the vial tested. Every size of ARA-290 is filled from the same tested batch, so this 10mg report covers 20mg and 30mg as well. The report supplied with your order carries a verification key you can check on Janoshik’s own site.

Purity99.000%
Measured content11.22 mg
BatchL77ara2901226
Verification key6RCBZADYIQHB

View & verify this report on Janoshik › · All lab reports ›

Related Compounds

Researchers working with ARA290 often work alongside the following compounds in the preclinical literature:

Scientific References & Sources

Chemical and reference data for ARA290 is drawn from public chemical registries (CAS, PubChem) and the independent peer-reviewed literature. All sources are third-party and independently verifiable; Lab77 Peptides is not affiliated with the cited publications or databases.