Cyclic 7-AA α-MSH analogue

MT-2 (Melanotan-II).

A 7-amino-acid cyclic synthetic analogue of alpha-MSH with a lactam bridge. Broad melanocortin receptor agonism.

Key Information

CompoundMelanotan 2 (MT-2)
Research categoryMelanocortin Research
Available sizes10mg
PricingFrom £39
FormatLyophilised powder in sealed vial
Purity>99% by HPLC (Janoshik Analytical, batch-verified)
Intended useIn-vitro laboratory research only. Not for human consumption.

Chemical & Reference Data

Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.

Compound classSynthetic 7-amino-acid cyclic α-MSH analogue (Melanotan II)
Molecular formulaC50H69N15O9
Molecular weight1024.18 g/mol
CAS Registry Number121062-08-6
PubChem CID92432
Number of residues7
Amino acid sequenceAc-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Receptor / mechanismNon-selective melanocortin receptor agonist (MC1R, MC3R, MC4R, MC5R).
Reported half-lifeReported ~30 minutes in human serum.
SolubilityLyophilised powder reconstitutes in bacteriostatic water for laboratory use.
Storage (lyophilised)Stable at 2–8 °C lyophilised for 24+ months.
Storage (reconstituted)Reconstituted: store at 2–8 °C, use within 14 days.
Clinical / regulatory statusInvestigational research compound.

Research Profile

  • Cyclic heptapeptide α-MSH analogue
  • Non-selective melanocortin agonist
  • MC1R/MC3R/MC4R/MC5R activity
  • Third-party purity tested
  • Research use only

Melanotan-2 is a synthetic cyclic heptapeptide analogue of α-MSH characterised in the literature as a non-selective melanocortin receptor agonist with activity at MC1R, MC3R, MC4R and MC5R. Supplied as lyophilised powder for in-vitro research use only.

The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.

Laboratory Handling

Melanotan 2 (MT-2) is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.

Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.

StateTemperatureShelf life
Lyophilised2–8 °C or −20 °CUp to 24 months
Reconstituted2–8 °C4–6 weeks typical

Purity & Verification

Every batch of Melanotan 2 (MT-2) we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.

Latest Janoshik report for MT-2 10mg · task #231382 · analysed 28 Sep 2026

This report is for the batch. Janoshik’s HPLC test measures what the compound is and how pure it is, and its quantification confirms the amount in the vial tested. The report supplied with your order carries a verification key you can check on Janoshik’s own site.

Purity99.390%
Measured content10.58 mg
BatchL77MT22612
Verification keyCVHMJMBK4ZJI

View & verify this report on Janoshik › · All lab reports ›

Related Compounds

Researchers working with Melanotan 2 (MT-2) often work alongside the following compounds in the preclinical literature:

Compare Melanotan 2 (MT-2) with Related Compounds

Scientific References & Sources

Chemical and reference data for MT2 is drawn from public chemical registries (CAS, PubChem) and the independent peer-reviewed literature. All sources are third-party and independently verifiable; Lab77 Peptides is not affiliated with the cited publications or databases.