7-AA ACTH(4-10) analogue
A 7-amino-acid synthetic peptide derived from the ACTH(4-10) fragment with a C-terminal Pro-Gly-Pro for enzymatic stability.
| Compound | Semax |
| Research category | Neuropeptide Research |
| Available sizes | 10mg, 20mg, 30mg |
| Pricing | From £28 |
| Format | Lyophilised powder in sealed vial |
| Purity | >99% by HPLC (Janoshik Analytical, batch-verified) |
| Intended use | In-vitro laboratory research only. Not for human consumption. |
Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.
| Compound class | Synthetic 7-amino-acid analogue of ACTH(4-10) |
| Molecular formula | C37H51N9O10S |
| Molecular weight | 813.93 g/mol |
| CAS Registry Number | 80714-61-0 |
| PubChem CID | 11765634 |
| Number of residues | 7 |
| Amino acid sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Receptor / mechanism | Modulator of melanocortin / BDNF expression pathways in literature. |
| Reported half-life | Reported short serum half-life; intranasal route discussed in literature. |
| Solubility | Lyophilised powder reconstitutes in bacteriostatic water for laboratory use. |
| Storage (lyophilised) | Stable at 2–8 °C lyophilised for 24+ months. |
| Storage (reconstituted) | Reconstituted: store at 2–8 °C, use within 14 days. |
| Clinical / regulatory status | Approved in Russia / CIS countries; investigational in research literature elsewhere. |
Semax is a synthetic heptapeptide derived from the N-terminal fragment of adrenocorticotropic hormone (ACTH 4-7) with a C-terminal Pro-Gly-Pro extension. Characterised in preclinical literature for its stability profile and effects on BDNF expression in rodent models. Supplied as lyophilised powder for in-vitro research use only.
The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.
Semax is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.
Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.
| State | Temperature | Shelf life |
|---|---|---|
| Lyophilised | 2–8 °C or −20 °C | Up to 24 months |
| Reconstituted | 2–8 °C | 4–6 weeks typical |
Every batch of Semax we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.
Latest Janoshik report for Semax 10mg · task #231375 · analysed 28 Sep 2026
This report is for the batch, not the size. Janoshik’s HPLC test measures what the compound is and how pure it is, and its quantification confirms the amount in the vial tested. Every size of Semax is filled from the same tested batch, so this 10mg report covers 20mg and 30mg as well. The report supplied with your order carries a verification key you can check on Janoshik’s own site.
| Purity | 98.915% |
| Measured content | 10.47 mg |
| Batch | L77semax2612 |
| Verification key | V694P1BU1G1B |
Researchers working with Semax often work alongside the following compounds in the preclinical literature:
Chemical and reference data for SEMAX is drawn from public chemical registries (CAS, PubChem) and the independent peer-reviewed literature. All sources are third-party and independently verifiable; Lab77 Peptides is not affiliated with the cited publications or databases.