Thymosin Beta-4 fragment
A synthetic fragment representing the active actin-binding region of full-length Thymosin Beta-4. Studied in tissue-repair and angiogenesis-related research.
| Compound | TB-500 |
| Research category | Regenerative Research |
| Available sizes | 10mg, 20mg, 30mg |
| Pricing | From £33 |
| Format | Lyophilised powder in sealed vial |
| Purity | >99% by HPLC (Janoshik Analytical, batch-verified) |
| Intended use | In-vitro laboratory research only. Not for human consumption. |
Reference data drawn from public databases (PubChem, UniProt) and peer-reviewed literature. For research and laboratory characterisation only.
| Compound class | Synthetic Thymosin β4 fragment (TB-500) |
| Molecular formula | C84H139N23O27 |
| Molecular weight | 1932.1 g/mol |
| CAS Registry Number | 77591-33-4 |
| PubChem CID | 16129697 |
| Number of residues | 17 |
| Amino acid sequence | 17-amino-acid fragment of thymosin beta-4 (residues 17-23 active region). |
| Receptor / mechanism | Actin-binding peptide; modulates angiogenesis pathways in literature. |
| Reported half-life | Reported short serum half-life in published preclinical literature. |
| Solubility | Lyophilised powder reconstitutes in bacteriostatic water for laboratory use. |
| Storage (lyophilised) | Stable at 2–8 °C lyophilised for 24+ months. |
| Storage (reconstituted) | Reconstituted: store at 2–8 °C, use within 14 days. |
| Clinical / regulatory status | Preclinical / investigational. |
TB-500 is a synthetic fragment of Thymosin Beta-4, a naturally occurring 43-amino-acid peptide characterised in the literature for its role in actin sequestration and cellular migration in preclinical models. Supplied as lyophilised powder for in-vitro research use only.
The above describes how this compound is characterised in the published peer-reviewed literature. It is not a claim about effects in humans.
TB-500 is supplied as a lyophilised (freeze-dried) powder in a sealed glass vial. For laboratory reconstitution, add the desired volume of diluent (typically bacteriostatic water) slowly down the side wall of the vial. Swirl gently until fully dissolved - do not vortex or shake. Store reconstituted solutions at 2–8 °C and use within 4–6 weeks.
Use our Reconstitution Volume Calculator to compute the resulting mg/ml concentration.
| State | Temperature | Shelf life |
|---|---|---|
| Lyophilised | 2–8 °C or −20 °C | Up to 24 months |
| Reconstituted | 2–8 °C | 4–6 weeks typical |
Every batch of TB-500 we supply is independently HPLC-verified by Janoshik Analytical. Where a Janoshik report has been issued for the current batch it is supplied with the order and carries a unique verification key that can be authenticated against Janoshik's records. Reported purity is consistently above 99%.
Latest Janoshik report for TB-500 10mg · task #208428 · analysed 6 Aug 2026
This report is for the batch, not the size. Janoshik’s HPLC test measures what the compound is and how pure it is, and its quantification confirms the amount in the vial tested. Every size of TB-500 is filled from the same tested batch, so this 10mg report covers 20mg and 30mg as well. The report supplied with your order carries a verification key you can check on Janoshik’s own site.
| Purity | 99.020% |
| Measured content | 10.96 mg |
| Batch | L77TB268 |
| Verification key | XNWZXL7BN3IK |
Researchers working with TB-500 often work alongside the following compounds in the preclinical literature:
Chemical and reference data for TB500 is drawn from public chemical registries (CAS, PubChem) and the independent peer-reviewed literature. All sources are third-party and independently verifiable; Lab77 Peptides is not affiliated with the cited publications or databases.